Meiotic recombination is focused within the genome by the creation of double-strand breaks (DSBs) at recombination ‘hotspots’. At least two mechanisms are identified to be concerned. Hoge et al. report that these mechanisms are usually not mutually unique and that variations between species within the recombination panorama replicate the steadiness of competitors between them.
The authors first improved the corn snake reference genome and the annotation of transcription begin websites and CpG islands. Genomes from 37 snakes have been sequenced, and 24 snakes that weren’t shut kinfolk have been analysed for SNPs. Using this genetic variation, patterns of linkage disequilibrium (LD) have been used to deduce a inhabitants recombination map of the genome.