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HomePet Industry NewsPet Travel NewsKondapa Naidu Bobba, PhD, provides JNM paper Highlighting Radiolabeling Methology

Kondapa Naidu Bobba, PhD, provides JNM paper Highlighting Radiolabeling Methology

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Kondapa Naidu Bobba, PhD, is very first author of “Evaluation of 134Ce/134La as an ANIMAL Imaging Theranostic Pair For 225Ac -Radiotherapeutics,” a Journal of Nuclear Medicine (JNM) short article released May 18 that goes over the advancement of a robust radiolabeling methology and used enhanced approach for making use of prostate cancer targeting representatives PSMA-617 and antibody YS5. Dr. Bobba, an assistant expert scientist in the UC San Francisco Department of Radiology & Biomedical Imaging, performed his research study examinations with PI Robert Flavell, MD, PhD, chief of Molecular Imaging and Therapeutics, and the matching author. Additional authors consisted of Henry VanBrocklin, PhD, Youngho Seo, PhD, along with associates from UCSF and the University of Virginia.

The JNM short article addresses the obstacle of dosing with the healing nuclide 225Ac due to low emission rates of imageable photons. “Imaging with 134Ce-identified radiopharmaceuticals have the possible to guide healing dosing of the concomitant 225Ac-identified particle,” compose Dr. Bobba et al. “Encouragingly, the ex-vivo biodistribution of 134Ce/225Ac-Macropa-PEG4-YS5 showed similar circulation in many tissues in addition to growths with the exception of the liver and spleen. To our understanding, this is the very first report as a biochemical research study comparing the biodistribution of Ce-134 and Ac-225, beginning with chelators to tumor-targeting vectors.”

Dr. Bobba provided his research study on May 23, 2023, at the International Symposium on Radiopharmaceutical Sciences (iSRS) yearly conference in Honolulu, Hawaii. He was chosen as a recipient of a UCSF Radiology & Biomedical Imaging Surbeck travel award to go to the conference. The award honors the memory of Sarah J. Nelson, PhD, a well-known UCSF Radiology research study researcher and professor who died in 2019. The Surbeck travel awards intend to support non-faculty academics performing research study in imaging science who are taking a trip to a conference for a welcomed discussion.

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