The collision occurred on the N25 Cork-Waterford street between Midleton and Castlemartyr shortly earlier than 8am.
It is known the collision concerned an articulated lorry and a automobile.
Initial experiences are that one motorist has been significantly injured.
The collision occurred close to Loughaderra townland.
Emergency providers space on the scene and a partial street closure has been carried out to facilitate the work of fireside brigade personnel and paramedics.
Gardaí burdened that diversions are in place through Mogeely with the N25 presently closed between Midleton and Castlemartyr.
Motorists have been urged to keep away from the world or to permit further time for his or her journeys given the site visitors diversions presently in place.
Two different collisions occurred in Cork at the moment although no critical accidents have been reported within the incidents exterior Castletownroche in north Cork and at Mahon close to the doorway to the Jack Lynch tunnel.