The Blues today invited both N’Golo Kante and Christian Pulisic back onto the training pitch however they did not finish the complete session and sign up with captain Cesar Azpilicueta, who continues to be kept an eye on for concussion, as not available for the London derby.
Young striker Armando Broja is most likely out for the season after knee surgical treatment, and Edouard Mendy is surrounding a return after suffering a damaged finger.
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So that suggests Potter needed to make some hard choices as he bids to get away a run that has actually seen Chelsea win simply 2 of their last 14 matches.
Reece James and Thiago Silva return after being rested, while Ben Chilwell gets approval over Marc Cucurella as Kalidou Koulibably is preferered to Benoit Badiashile.
Ruben Loftus-Cheek begins along with Enzo Fernandez, while Hakim Ziyech finishes an enforcing front 4 of Joao Felix, Kai Havertz and Raheem Sterling.
Confirmed group news
Tottenham XI: Forster, Romero, Dier, Lenglet, Emerson, Skipp, Hojbjerg, Davies, Kulusevski, Richarlison, Kane
Subs: Sanchez, Son, Perisic, Danjuma, Porro, Tanganga, Lucas, Sarr, Austin
Chelsea XI: Kepa, James, Thiago Silva, Koulibaly, Chilwell, Loftus-Cheek, Fernandez, Ziyech, Joao Felix, Sterling, Havertz
Subs: Badiashile, Aubameyang, Bettinelli, Mudryk, Mount, Zakaria, Gallagher, Madueke, Fofana