A examine of malpractice lawsuits associated to lively surveillance for prostate most cancers discovered “no proof of profitable malpractice litigation,” main the authors to conclude that lively surveillance “represents a sound administration possibility in acceptable low-risk cancers.” (Annals of Surgery)
Some veterans uncovered to Agent Orange and different toxins have been denied advantages from the Veterans Administration for cancers and different sickness linked to the toxins. (KFF Health News)
The FDA has issued three draft steering paperwork that make suggestions to develop eligibility for most cancers scientific trials. (Regulatory Focus)
Trastuzumab deruxtecan (Enhertu) considerably improved progression-free survival in a randomized examine of hormone receptor-positive, HER2-low metastatic breast most cancers after no less than one line of endocrine remedy, AstraZeneca introduced.
The FDA accredited the sixth biosimilar to trastuzumab (Herceptin), trastuzumab-strf (Hercessi), for HER2-positive breast and abdomen cancers, Accord BioPharma introduced.
Meanwhile, Sandoz resolved a patent dispute over its biosimilars to Amgen’s denosumab (Prolia, Xgeva). (Reuters)
Merck introduced that the section III KEYNOTE-811 trial confirmed important enchancment in progression-free and total survival in HER2-positive abdomen most cancers handled with pembrolizumab (Keytruda), trastuzumab, and platinum-based chemotherapy.
In a sequence of laboratory research, including a ketogenic dietary complement to most cancers remedy considerably improved anti-cancer exercise in a mannequin of prostate most cancers. (University of Notre Dame)
Cancer mortality is 2 to a few occasions larger amongst Native Hawaiian and different Pacific Islander Americans, in response to a report from the American Cancer Society.
An investigational blood check confirmed potential for figuring out sufferers with an elevated danger of liver most cancers, years earlier than precise prognosis. (Mass General Brigham, Beth Israel Deaconess Medical Center)