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Disease X: UK vaccine center getting ready for the next pandemic

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Preparations are being made in case another pandemic strikes. (Picture: Michael Gillen)

Preparations are being made in case another pandemic strikes. (Picture: Michael Gillen)

An advanced vaccine research study center, where researchers will work to make sure future pandemics are dropped in their tracks and do not cause the same disruption to everyday life as Covid-19, has actually been revealed by the federal government.

The Vaccine Development and Evaluation Centre (VDEC) is based at the UK Health and Security Agency (UKHSA) science and defence innovation school Porton Down, near Salisbury in Wiltshire.

Live viruses will be kept on-site in specialist containment facilities, with scientists taking a look at pathogens that do not yet have a vaccine, or ones where immunisation might be enhanced, such as influenza, mpox or hantavirus.

EMBARGOED TO 0001 MONDAY AUGUST 7
File photo dated 25/02/21 of the Dstl high containment lab building at Porton Down in Salisbury, Wiltshire. A state-of-the-art vaccine research facility, where scientists will work to ensure future pandemics are stopped in their tracks and do not cause the same disruption to everyday life as Covid-19, has been unveiled by the Government. Issue date: Monday August 7, 2023. PA Photo. The Vaccine Development and Evaluation Centre (VDEC) is based at the UK Health and Security Agency (UKHSA) science and defence technology campus Porton Down, near Salisbury in Wiltshire. Live viruses will be kept on-site in specialist containment facilities, with researchers looking at pathogens that do not yet have a vaccine, or ones where immunisation could be improved, such as flu, mpox or hantavirus. See PA story HEALTH Vaccines. Photo credit should read: Ben Birchall/PA Wire

EMBARGOED TO 0001 MONDAY AUGUST 7 File picture dated 25/02/21 of the Dstl high containment laboratory building at Porton Down in Salisbury, Wiltshire. An advanced vaccine research study center, where researchers will work to make sure future pandemics are dropped in their tracks and do not trigger the exact same interruption to daily life as Covid-19, has actually been revealed by the Government. Issue date: Monday August 7, 2023. PA Photo. The Vaccine Development and Evaluation Centre (VDEC) is based at the UK Health and Security Agency (UKHSA) science and defence innovation school Porton Down, near Salisbury in Wiltshire. Live infections will be kept on-site in professional containment centers, with scientists taking a look at pathogens that do not yet have a vaccine, or ones where immunisation might be enhanced, such as influenza, mpox or hantavirus. See PA story HEALTH Vaccines. Photo credit must check out: Ben Birchall/PA Wire

Elsewhere, researchers will test emerging Covid-19 jabs on brand-new variations, target illness such as tuberculosis (TB), and are presently running stage one scientific trials on a prospective world-first jab versus Crimean-Congo haemorrhagic fever, a tick-borne infection which is deadly in about 30 percent of cases.

Professor Dame Jenny Harries, president of UKHSA, said: “What we’re trying to do now is capture that really excellent work from Covid and make sure we’re using that as we go forward for any new pandemic threats.”

It is likewise hoped the center will help the UK take on “disease X” by boosting readiness for yet-to-be recognized pathogens with pandemic capacity.

Scientists will take a look at viruses and bacteria they already know pose a threat and assess the efficiency of existing vaccines versus them.

Dame Jenny said the term “disease X” is used as researchers “don’t know what the next pathogen will be that will cause a pandemic” however said the UK requirements “to be ready”.

She included: “We don’t know what it is but we can get ready for some virus families.

“We can guess a little bit; we can look at changing the epidemiology of different viruses, we can look at changing climate and start to estimate, but we will never know 100%.

“What we try to do here is keep an eye on the ones that we do know. For example with Covid, we are still here testing all the new variants with the vaccines that have been provided to check they are still effective.

“But we are also looking at how quickly we can develop a new test that would be used if a brand new virus popped up somewhere.”

The World Health Organisation (WHO) has actually been keeping a close eye on present bird influenza break outs.

Currently, the infection is not infectious amongst human beings – although it has actually infected some mammals. Dr Sylvie Briand, director of epidemic and pandemic readiness and avoidance, says there is no requirement for panic however has actually advised nations to be watchful.

“With the info available up until now, the infection does not seem able to send from someone to another quickly, however watchfulness is required to recognize any development in the infection that can alter that,” she said.

“WHO is working carefully with FAO and WOAH, and lab networks to keep track of the development of these infections, searching for signals of any modification that might be more unsafe to human beings. We motivate all nations to increase their capability to keep track of these infections and to find any human cases. This is specifically essential as the infection is now impacting nations with minimal previous experience in bird influenza monitoring.”

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