Thursday, July 18, 2024
Thursday, July 18, 2024
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ASPR’s Response to H5N1 Bird Flu


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H5N1 hen flu is widespread in wild birds worldwide and is inflicting outbreaks in poultry and U.S. dairy cows. While the
present public well being danger is low, the HHS Administration for Strategic Preparedness and Response (ASPR) is monitoring the scenario intently and making assets available to assist state, native, tribal, and territorial companions.

ASPR has a number of preparedness parts in place to assist keep forward of the H5N1 virus that’s infecting cows. ASPR has private protecting gear (PPE) and antiviral medicine available within the Strategic National Stockpile (SNS). The
National Pre-pandemic Influenza Vaccine Stockpile (NPIVS), managed by the Biomedical Advanced Research and Development Authority, accommodates pre-pandemic influenza vaccine “building blocks” within the type of bulk antigens, the a part of vaccine that triggers the immune system to guard towards the virus; and adjuvants which cut back the quantity of antigen wanted to set off an immune response.

Avian Influenza H5N1 - NIAID


The SNS maintains a big stock of PPE that could be requested to guard well being care professionals. SNS can also be providing the next forms of
PPE for workers on farms or associated industries the place cattle or different contaminated animals are current: face shields, gloves, NIOSH-approved N95 respirators, elastomeric half-mask respirators, and goggles.

ASPR’s mission is to assist the nation put together for, reply to, and recuperate from public well being emergencies and disasters. The SNS contributes to this mission because the nation’s largest repository of emergency medical provides. While many states maintain massive provides of PPE in state-held stockpiles, if these stockpiles of PPE are depleted or unavailable, federal provides managed by SNS could also be requested. The HHS Secretary’s Operations Center (SOC) is the preliminary contact for requesting emergency provides. The SOC is staffed by ASPR 24 hours a day, 7 days per week, and one year a 12 months. More info might be discovered at:
Requesting SNS Assets. PPE can also be obtained through the business market via the conventional provide chain.


NPIVS holds an array of pre-pandemic bulk antigens to guard towards influenza viruses with pandemic potential. The NPIVS maintains adequate uncooked supplies to quickly formulate sufficient vaccine doses to immunize essential care employees and at-risk populations through the early phases of a response. The authorities has the uncooked materials to make tens of millions of extra doses inside weeks, with extra to return within the following months. At this time, ASPR is supporting the availability of vaccines if they’re wanted.


The SNS accommodates tens of millions of therapy programs of antiviral medicine, together with Tamiflu (oseltamivir), an antiviral drug that treats seasonal flu and is predicted to work towards H5N1. Tamiflu could cut back the severity of an infection if the medication is taken shortly after the affected person is symptomatic.

ASPR will make Tamiflu available upon request to jurisdictions that do not need their very own stockpiles and are offering assets to assist the therapy of symptomatic individuals with publicity to birds, cattle, or different animals with confirmed or suspected H5N1 an infection. Tamiflu and generic oseltamivir are additionally available via the conventional business provide chain.

Technical Assistance from ASPR TRACIE

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